Targeting the Immunogenetic Diseases with the Appropriate HLA Molecular Typing: Critical Appraisal on 2666 Patients Typed in One Single Centre

Table 3

Allele frequencies of HLA genes correlated to autoimmune pathologies in adult bone marrow donors (BMD), cord blood donors (CBD), Behçet’s disease (BD), rheumatoid arthritis (RA), celiac disease (CD), insulin-dependent diabetes mellitus (IDDM), and shared epitope (SE).

HLA susceptibility alleles	BMD	CBD	Uveitis	BD	RA	CD	IDDM
HLA-B*27	1.7%	2.15%	8.40%
HLA-B*51	12.91%	9.88%		15.57%
SE alleles; (HLA-DRB1*01:01, *01:02, *04:01, *04:04, *04:05, *04:08, *10:01, *14:02)	10.85%	13.48%			13.72%
HLA-DQB1*02:01	9.37%	7.92%				21.76%	17.19%
HLA-DQB1*02:02	8.99%	9.98%				17.61%
HLA-DQB1*03:02	4.38%	5.93%				6.10%	14.45%