Inflammatory Bowel Disease Therapies and Gut Function in a Colitis Mouse Model

Table 2

Mucosal-to-serosal ¹HRP permeability flux.

Groups	Week 2			Week 4
	HRP flux (nM/hr)	^2𝑃	^3𝑃	HRP flux (nM/hr)	^2𝑃	^3𝑃
Infected controls	150 ± 9	<0.01	—	141 ± 17	<0.01	—
^4HC	120 ± 9	<0.01	<0.05	118 ± 5	<0.01	<0.01
^5EEN	89 ± 8	NS	<0.01	90 ± 10	NS	<0.01
^6MNZ	99 ± 3	NS	<0.05	85 ± 11	NS	<0.01
EEN + MNZ	87 ± 6	NS	<0.01	86 ± 10	NS	<0.01

¹Horseradish peroxidase.
Data are mean values ± SD.
 ²𝑃 versus noninfeced controls (HRP flux: 102 ± 9 nM/hr).
 ³𝑃 versus infected controls.
Significant 𝑃 values are in bold (𝑃≤0.05).
NS: not significant; 𝑃>0.05.
⁴Hydrocortisone; ⁵exclusive enteral nutrition; ⁶metronidazole.