Inflammatory Bowel Disease Therapies and Gut Function in a Colitis Mouse Model

Table 3

Spearman’s correlation values for markers of inflammation with ¹HRP flux and with mucosal MLCK gene expression.

Correlation parameters	^2MIP-2	^3LIX	^4TNF-𝛼
HRP	Noninfeced controls: 𝑟=0.61, 𝑃=0.03	Noninfeced controls: 𝑟=0.78, 𝑃<0.01	Noninfeced controls: 𝑟=0.74, 𝑃<0.01
	Infected controls: 𝑟=0.68, 𝑃<0.01	Infected controls: 𝑟=0.71, 𝑃<0.01	Infected controls: 𝑟=0.75, 𝑃<0.01
	^5HC: 𝑟=81, 𝑃<0.01	HC: 𝑟=0.52, 𝑃=0.03	HC: 𝑟=0.77, 𝑃<0.01
	^6EEN: 𝑟=0.80, 𝑃<0.01	EEN: 𝑟=0.53, 𝑃=0.04	EEN: 𝑟=0.88, 𝑃<0.01
	^7MNZ: 𝑟=0.72, 𝑃<0.01	MNZ: 𝑟=0.68, 𝑃=0.01	MNZ: 𝑟=0.69, 𝑃<0.01
	EEN + MNZ: 𝑟=0.71, 𝑃<0.01	EEN + MNZ: 𝑟=0.84, 𝑃<0.01	EEN + MNZ: 𝑟=0.63, 𝑃<0.01
^8MLCK	Noninfeced controls: 𝑟=0.82, 𝑃<0.01	Noninfeced controls: 𝑟=0.69, 𝑃<0.01	Noninfeced controls: 𝑟=0.79, 𝑃<0.01
	Infected controls: 𝑟=0.73, 𝑃<0.01	Infected controls: 𝑟=0.66, 𝑃=0.01	Infected controls: 𝑟=85, 𝑃<0.01
	HC: 𝑟=0.67,𝑃=0.01	HC: 𝑟=0.84, 𝑃<0.01	HC: 𝑟=0.76, 𝑃<0.01
	EEN: 𝑟=0.75, 𝑃<0.01	EEN: 𝑟=0.64, 𝑃=0.02	EEN: 𝑟=0.78, 𝑃<0.01
	MNZ: 𝑟=0.59, 𝑃=0.01	MNZ: 𝑟=0.77, 𝑃<0.01	MNZ: 𝑟=0.63, 𝑃=0.01
	EEN + MNZ: 𝑟=0.68, 𝑃<0.01	EEN + MNZ: 𝑟=0.71, 𝑃<0.01	EEN + MNZ: 𝑟=0.69, 𝑃<0.01

¹Horseradish peroxidase; ²macrophage inflammatory protein 2; ³lipopolysaccharide-induced CXC chemokine; ⁴tumor necrosis factor 𝛼; ⁵hydrocortisone; ⁶exclusive enteral nutrition; ⁷Metronidazole. ⁸myosin light chain kinase.