A Quantitative Analysis of the Impact on Chromatin Accessibility by Histone Modifications and Binding of Transcription Factors in DNase I Hypersensitive Sites
Redundancy of HM features and TF binding features. (a) Scatter plot of predicted versus experimentally measured DNase-seq signals using all HM and TF binding features. The black line represents the linear fit between predicted and measured signals (, coefficient of determination). (b) Comparison of prediction powers (, the square root of coefficient of determination) between all possible one-feature, two-feature, three-feature models, and the full model in H1hesc.
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