Clinical Study

Calcifications of Vertebrobasilar Arteries on CT: Detailed Distribution and Relation to Risk Factors in 245 Ischemic Stroke Patients

Table 1

Demographic characteristics of ischemic stroke patients overall and grouped by vertically dispersed calcifications.

All ( )No vertically dispersed calcifications ( )Vertically dispersed calcifications ( )

Age (years)79.0 (71.0–84.0)78.0 (70.5–85.5)79.0 (72.0–84.0)
Female141 (57.6)71 (71.0)70 (48.3)
Prior stroke54 (22.0)21 (21.0)33 (22.8)
Arterial hypertension186 (75.9)75 (75.0)111 (76.6)
Diabetes mellitus51 (20.8)15 (15.0)36 (24.8)
Atrial fibrillation51 (20.8)17 (17.0)34 (23.4)
Heart failure46 (18.8)17 (17.0)29 (20.0)
Statin therapy60 (24.5)17 (17.0)43 (29.7)
Transitory ischemic attack16 (6.5)3 (3.0)13 (9.0)
Previous TIA/stroke68 (27.8)23 (23.0)45 (31.0)
Myocardial infarction16 (6.5)4 (4.0)12 (8.3)
Peripheral arterial occlusive disease14 (5.7)4 (4.0)10 (6.9)
Artificial heart valve4 (1.6)2 (2.0)2 (1.4)
Carotid arteries disease8 (3.3)2 (2.0)6 (4.1)
Carotid arteries intervention3 (1.2)1 (1.0)2 (1.4)
Smoking history*59 (24.1)21 (21.0)38 (26.2)
OCSP classification
 TACI47 (19.2)14 (14.0)33 (22.8)
 PACI144 (58.8)60 (60.0)84 (57.9)
 LACI1 (0.4)0 (0.0)1 (0.7)
 POCI50 (20.4)25 (25.0)25 (17.2)
 UNK3 (1.2)1 (1.0)2 (1.4)
TOAST classification
 LAA42 (17.1)14 (14.0)28 (19.3)
 CAE83 (33.9)32 (32.0)51 (35.2)
 SAO18 (7.3)10 (10.0)8 (5.5)
 UND102 (41.6)44 (44.0)58 (40.0)
Cholesterol (mmol/L)
LDL (mmol/L)
HDL (mmol/L)
Creatinine ( mol/L)

Data presented as number (percentages), median (quintiles), or means ± standard deviation.
Smoking history unknown in 61/245 (24.9%) of patients. LDL: low density lipoprotein cholesterol. HDL: high density lipoprotein cholesterol. LAA: large artery atherosclerosis, CAE: cardioembolic, SAO: small artery occlusion, UND: undetermined. TACI: total anterior circulation infarct, PACI: partial anterior circulation infarct, LACI: lacunar cerebral infarct, POCI: posterior circulation infarct, UNK: unknown site of the infarct.