BioMed Research International / 2013 / Article / Fig 5

Research Article

Different Effects of the Immunomodulatory Drug GMDP Immobilized onto Aminopropyl Modified and Unmodified Mesoporous Silica Nanoparticles upon Peritoneal Macrophages of Women with Endometriosis

Figure 5

The influence of free GMPD and GMPD, immobilized on different silica nanoparticles, upon the MMP-9 and TIMP-1 mRNAs expression by peritoneal macrophages of women with endometriosis. (a) The influence of GMPD on MMP-9 mRNA expression. (b) The influence of GMDP on TIMP-1 mRNA expression. (Notes: C—control (incubation in RPMI 1640 medium only), GMDP—free form of GMDP, AMNPs-GMDP, immobilized onto the AMNPs, UMNPs-GMDP, immobilized onto the UMNPs, results are presented as the mean ± standard error; *differences in comparison to the control values are statistically significant, ).