Research Article

A Case-Control Study between Gene Polymorphisms of Polyunsaturated Fatty Acid Metabolic Rate-Limiting Enzymes and Acute Coronary Syndrome in Chinese Han Population

Table 4

Distribution of genotype frequencies of SNPs in case and control groups.

GenesSNPsGenotypeCase (%)Control (%) OR95% CI

FADS1 rs174556C/C96 (38.6)119 (49.6)6.0840.036a
C/T110 (44.2)96 (40.0)0.826a0.418–1.459a
T/T43 (17.3)25 (10.4)0.324a0.126–0.864a

FADS2 rs174617T/T148 (59.4)149 (62.1)0.4100.815
C/T90 (36.1)82 (34.2)1.1050.759–1.609
C/C11 (4.4)9 (3.8)1.2300.495–3.056

ELOVL2 rs3756963T/T141 (56.6)145 (60.4)2.3010.317
C/T86 (34.5)82 (34.2)1.0790.737–1.579
C/C22 (8.8)13 (5.4)1.7400.844–3.589

aAdjustment for age, sex, and the presence of diabetes, hypertension, and smoking by forward logistic regression analysis.