Antioxidant, Lipid Lowering, and Membrane Stabilization Effect of Sesamol against Doxorubicin-Induced Cardiomyopathy in Experimental Rats

Table 2

Effect of sesamol on serum LDH, CK, AST, and troponin-T.

Group	LDH IU/L	CK IU/L	AST IU/L	Troponin-T µg/mL
G1: control	109.2±6.493	114.3±6.766	121.5±2.9	0.50±0.21
G2: sesamol (50 mg/kg)	119.0±2.309	128.3±1.7	138.0±0.89	0.59±0.34
G3: DOX (15 mg/kg in 6-divided dose)	299.0±20.67^a	249.3±4.2^a	345.0±17.8^a	1.7±0.63^a
G4: DOX+sesamol	107.5±5.696^b	185.7±0.88^b	119.0±16.9^b	0.81±0.14^b

All values expressed as mean ± SD. ^a𝑃<0.0001 versus G1. ^b𝑃<0.0001 versus G3.