Radioprotective Effects of Gallic Acid in Mice

Table 1

Effect of oral administration of gallic acid (GA) on the induction of individual chromosomal aberrations, polyploidy, SDC, pulverization, and number of aberrations per cell in mouse bone marrow cells by whole body gamma irradiation (2 Gy).

Treatments	Breaks (%)	Ring (%)	Dicentric (%)	Aberrations/cell	Pulverisation	Polyploidy	SDC
Normal	1.4 ± 0.89	0 ± 0	1 ± 0.58	0.024 ± 0.015	0 ± 0	0 ± 0	0 ± 0
GA	1.2 ± 1.09^ns	0 ± 0^ns	0.8 ± 0.84^ns	0.02 ± 0.019^ns	0 ± 0^ns	0 ± 0^ns	0 ± 0^ns
2 Gy	29.8 ± 2.89	8.7 ± 2.59	10.5 ± 0.47	0.49 ± 0.04	2.4 ± 0.81	5.6 ± 0.5	1.6 ± 0.46
GA + 2 Gy	9 ± 0.71^$	3 ± 0.70^$	2.5 ± 0.35^$	0.145 ± 0.02^$	0 ± 0^$	1 ± 0^$	0 ± 0^$

ns: not significant, $: P < 0.001, when compared with respective controls.