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BioMed Research International
Volume 2013 (2013), Article ID 961751, 9 pages
Research Article

A Randomized Controlled Trial of Two Different Lengths of Nicotine Replacement Therapy for Smoking Cessation

1School of Public Health, Guangxi Medical University, Nanning, Guangxi, China
2Department of Medicine, Boston Medical Center, Boston University Medical Campus, Boston, MA 02118, USA
3Department of Community Medicine, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
4School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong

Received 26 April 2013; Revised 30 July 2013; Accepted 1 August 2013

Academic Editor: Ronald Ma

Copyright © 2013 Abu S. Abdullah et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This study examined if 2-week free nicotine replacement therapy (NRT) would be more effective than 1-week free NRT to help smokers quit smoking at 6 and 12 months. In a single-blinded randomized controlled trial design, 562 Chinese smokers who attended a smoking cessation clinic in Hong Kong, China, were randomly allocated into two groups (A1 and A2): A1 ( ) received behavioural counselling with free NRT for 1 week; A2 ( ) received similar counselling with free NRT for 2 weeks. All subjects received printed self-help materials to support their quitting efforts. A structured questionnaire was used for data collection, including pattern of NRT use and self-reported 7-day point prevalence quit rate at 6 months and 12 months. Among the participants, the mean number of cigarettes smoked per day was 18.8 ( ). By intention-to-treat analysis, 7-day point prevalence quit rates were not significantly different between A1 and A2 groups at 6-month (27.5% versus 27.3%; ) and 12-month (21.1% versus 21.2%; ) followup. The findings suggest that two-week free NRT was not more effective than 1-week free NRT to increase smoking cessation rate among Chinese smokers.