Function of the p38MAPK-HSP27 Pathway in Rat Lung Injury Induced by Acute Ischemic Kidney Injury

Table 3

TNF-𝛼, IL-6 concentration in rat’s serum and BALF (pg/mL, 𝑥±𝑠, 𝑛=6).

Time; (h)	Plasma			BALF
	A	B	C	A	B	C
TNF-𝛼
0	133.9±13.7	133.9±13.7	133.9±13.7	68.6±11.7	68.6±11.7	68.6±11.7
2	203.5±14.7	500.8±23.6^∗	253.3±20.7^#	76.7±31.6	130.17±25.6^∗	86.5±21.5^#
4	300.6±13.9	615.0±21.0^∗	431.7±22.3^#	83.7±21.7	173.33±38.5^∗	103.5±32.5^#
6	367.1±12.7	754.2±59.3^∗	493.6±50.5^#	91.3±27.8	207.17±29.5^∗	136.8±26.2^#
8	416.8±22.6	838.1±30.6^∗	535.0±28.3^#	106.7±23.4	258.33±34.4^∗	176.2±32.6^#
IL-1𝛽
0	9.16±1.47	9.16±1.47	9.16±1.47	5.17±1.47	5.17±1.47	5.17±1.47
2	13.00±1.96	28.17±1.33^∗	10.2±3.65^#	7.83±1.94	16.33±3.68^∗	10.63±2.39^#
4	15.50±1.84	47.17±2.34^∗	16.7±2.18^#	9.67±2.07	29.00±3.92^∗	15.38±3.64^#
6	18.83±1.75	71.83±4.76^∗	26.2±3.21^#	10.33±3.21	40.17±4.38^∗	19.26±5.21^#
8	25.33±2.33	92.16±5.31^∗	36.2±2.95^#	12.00±2.16	51.33±6.16^∗	23.56±2.91^#
IL-6
0	216.2±12.5	216.2±12.5	216.2±12.5	112.6±13.6	112.6±13.6	112.6±13.6
2	260.6±11.6	417.5±35.3^∗	296.5±33.6^#	128.3±19.4	220.3±37.8^∗	180.4±23.6^#
4	320.2±20.4	617.3±45.4^∗	356.7±45.1^#	166.7±32.7	339.0±32.2^∗	220.6±25.6^#
6	383.7±27.2	703.5±57.6^∗	433.5±36.5^#	193.3±25.6	450.1±50.8^∗	290.5±36.8^#
8	413.2±32.5	816.9±66.6^∗	523.6±42.6^#	260.0±40.0	571.3±76.6^∗	350.3±24.8^#
IL-10
0	23.16±3.64	23.16±3.64	23.16±3.64	10.91±5.47	10.91±5.47	10.91±5.47
2	25.00±4.26	58.17±2.33^∗	50.98±5.23	12.83±1.94	21.33±3.78^∗	19.32±2.93
4	27.50±3.04	67.17±6.14^∗	65.73±4.35	16.67±3.07	29.00±3.52^∗	26.37±4.36
6	31.83±4.72	71.83±5.56^∗	69.32±762	16.33±5.61	26.17±3.08^∗	23.12±3.61
8	35.33±5.73	62.16±6.61^∗	60.42±5.26	11.00±4.00	21.33±4.26^∗	19.12±4.02

Note. ∗Compared with Group A, 𝑃<0.05; #compared with Group B, 𝑃<0.05. Note: ∗compared with Group A, 𝑃<0.05; #compared with Group B, 𝑃<0.05.