Neuroprotective Activity of Thioctic Acid in Central Nervous System Lesions Consequent to Peripheral Nerve Injury
Figure 1
TBARS levels in plasma, expressed as μM of malondialdehyde (a), and activity of SOD in plasma, expressed as U/mL (b). (A) Control Sham-operated WKY rats; (B) control Sham-operated SHRs; (C) control CCI SHRs; (D) CCI SHRs treated with ()-thioctic acid 250 μmol/kg/day; (E) CCI SHRs treated with ()-thioctic acid 125 μmol/kg/day; (F) CCI SHRs treated with (+)-thioctic acid 125 μmol/kg/day; (G) CCI SHRs treated with (−)-thioctic acid 125 μmol/kg/day; (H) CCI SHRs treated with pregabalin 300 μmol/kg/day. * versus WKY control rats; ** versus SHR Sham-operated control rats; *** versus control CCI SHR.
