Heat Shock Protein 72 Expressing Stress in Sepsis: Unbridgeable Gap between Animal and Human Studies—A Hypothetical “Comparative” Study
Table 2
(a) Human in vivo studies relating intra- or extracellular Hsp72 (Hsp70) expression to outcome in sepsis. (b) Human in vitro studies relating intracellular Hsp72 (Hsp70) expression to outcome in sepsis.
Preconditioning of myeloid cells after LTA addition with rHsp70 (1)
Effect of human recombinant Hsp70 isolated from Spodoptera cells on neutrophil apoptosis and expression of CD11b/CD18 receptors and TNF on ROS production in neutrophils and monocytes
Ameliorated reactive oxygen species, TNF-, CD11b/CD18, did not normalize apoptosis (1)