Relationship between CCR and NT-proBNP in Chinese HF Patients, and Their Correlations with Severity of HF

Table 6

Cut-off points, sensitivity, specificity, and area under the curves for biomarkers and NYHA classification.

Marker	NYHA classification	Cut-off point	Sensitivity	Specificity	Area under ROC curve	SE	value	95% CI
								Lower	Upper
NT-proBNP	1-2	329.05 pg/mL	81.07%	75.62%	0.90	0.02	0.00	0.86	0.94
	3-4	324.40 pg/mL	82.34%	85.90%	0.92	0.02	0.00	0.89	0.96
CCR	1-2	61.39 mL/min	74.71%	63.02%	0.86	0.03	0.00	0.81	0.91
	3-4	63.13 mL/min	82.42%	78.33%	0.88	0.02	0.00	0.85	0.92

CCR: creatinine clearance rate; CI: confidence interval; NT-proBNP: N-terminal pro-B-type natriuretic peptide; NYHA: New York Heart Association; ROC: receiver operating characteristic; SE: standard error.