The Proximal Medial Sural Nerve Biopsy Model: A Standardised and Reproducible Baseline Clinical Model for the Translational Evaluation of Bioengineered Nerve Guides

Table 2

List of sensory testing.

Multimodal sensory testing
Sensory modality	Testing strategy	Unit/scale
Clinical evaluation	(Delayed wound healing, redness, swelling, pus, seroma, hypertrophic scarring, allergy, and foreign body sensation)
(1) Nociception	Visual Analog Scale (VAS) used for pain estimation	Value: 0–10
(2) Loss of sensation (hypesthesia)	Measurement and photo documentation of the area on the lateral aspect of the foot with loss of sensation	Value: cm^2
	Sharp-blunt discrimination	Value: yes/no
(3) Tinel’s sign	Palpation revealing Tinel’s sign and documentation of location in relation to the landmarks	Value: relationship to landmarks in cm
(4) Spatial resolution	Static and moving/dynamic two-point discrimination	Value: s/m 2-PD in mm
(5) Pressure	Semmes-Weinstein monofilament test	Value: monofilament strength in g
(6) Thermoception	Cold-warm discrimination	Value: yes/no
(7) Vibration	128 Hz tuning fork	Value: scale from 0–8