BioMed Research International / 2014 / Article / Tab 4

Clinical Study

Comparative Diagnostic Accuracy of Ganglion Cell-Inner Plexiform and Retinal Nerve Fiber Layer Thickness Measures by Cirrus and Spectralis Optical Coherence Tomography in Relapsing-Remitting Multiple Sclerosis

Table 4

Standardized correlation coefficients between OCT measurements and neurologic and visual function parameters in eyes of patients with relapsing-remitting multiple sclerosis, calculated using generalized estimating equations accounting for sex, age, and within-patient intereye correlation ().

BCVAMDEDSSDisease duration

Cirrus average pRNFL0.286*0.418*−0.014−0.233
Cirrus temporal pRNFL−0.0130.0620.001−0.141
Spectralis average pRNFL0.314*0.360*0.033−0.228
Spectralis temporal pRNFL0.1220.268−0.101−0.261
Spectralis PMB pRNFL0.1250.209−0.066−0.275
GCIPL average0.226*0.513*−0.178−0.262
GCIPL minimum0.2040.412*−0.161−0.299

Non-ON eyes ( = 104)
Cirrus average pRNFL−0.0190.0980.033−0.253
Cirrus temporal pRNFL−0.270−0.030−0.046−0.146
Spectralis average pRNFL0.210*0.1450.109−0.274
Spectralis temporal pRNFL−0.0250.093−0.092−0.284
Spectralis PMB pRNFL0.0020.083−0.040−0.332
GCIPL average−0.0620.109−0.113−0.297
GCIPL minimum0.0290.138−0.092−0.314

ON eyes ( = 36)
Cirrus average pRNFL0.1880.161−0.1730.012
Cirrus temporal pRNFL−0.0430.0010.105−0.013
Spectralis average pRNFL0.1750.149−0.1510.109
Spectralis temporal pRNFL0.1120.030−0.1950.065
Spectralis PMB pRNFL0.059−0.022−0.1200.097
GCIPL average0.1450.133−0.429−0.079
GCIPL minimum0.1440.120−0.421−0.227

; ; .
OCT: optic coherence tomography; BCVA: best corrected visual acuity; MD: Goldman 24-2 SITA standard visual field mean deviation; EDSS: Expanded Disability Status Scale; pRNFL: peripapillary retinal nerve fiber layer; PMB: papillomacular bundle; GCIPL: ganglion cell and inner plexiform layers; ON: optic neuritis.