Mesenchymal Stem Cells Expressing Brain-Derived Neurotrophic Factor Enhance Endogenous Neurogenesis in an Ischemic Stroke Model
Apoptotic cells identified using TUNEL staining. (a) Fewer TUNEL-positive cells were detected in rats transplanted with MSCs-BDNF compared with the other groups (MSCs or PBS) (TUNEL: green; DAPI: blue; scale bar: 50 μm). (b) The percentage of TUNEL-positive cells in the ischemic lesion was significantly reduced in the MSCs-BDNF group compared with the other groups (* and **).
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