Clinical Study

The Different Dose-Volume Effects of Normal Tissue Complication Probability Using LASSO for Acute Small-Bowel Toxicity during Radiotherapy in Gynecological Patients with or without Prior Abdominal Surgery

Table 1

Characteristics of patients.

Group 0 ( )
Number (%)
Group 1 ( )
Number (%)
value

Age (y)0.031
 Mean60.154.9
 Range29–9032–75
 <5016 (26)9 (26)
 51–6018 (30)15 (45)
 61–7011 (18)9 (26)
 >7016 (26)1 (3)
BMI0.360
 Mean24.925.7
 Range16.6–35.120.1–34.5
 <208 (13)0 (0)
 20–2627 (44)20 (59)
 >2626 (43)14 (41)
Stage0.007
 I-II 52 (85)19 (56)
 III-IV/recurrent9 (15) 15 (44)
Diabetes0.763
 No52 (85)30 (88)
 Yes9 (15)4 (12)
Hypertension0.779
 No50 (82) 29 (85)
 Yes11 (18) 5 (15)
Chemoradiotherapy0.013
 No15 (25) 17 (50)
 Yes46 (75)17 (50)
External beams doses (Gy)0.469
 WP 19.8, PM/LP 32.40 (0)1 (2.9)
 WP 39.620 (33)5 (14.7)
 WP 39.6, PM/LP 4527 (44)23 (67.6)
 WP 39.6, LP 50.40 (0)2 (5.9)
 WP 454 (7)1 (2.9)
 WP 45, PM/LP 50 410 (16)2 (5.9)

Group 0: patients without prior abdominal surgery; group 1: patients with prior abdominal surgery; BMI: body mass index; WP: whole pelvis; LP: low pelvis; PM: parametrium.
Differences between the group 0 and group 1 cohort were described with an independent sample -test for continuous variables and chi-square test for dichotomous variables.