Alleviation of Plasma Homocysteine Level by Phytoestrogen -Zearalanol Might Be Related to the Reduction of Cystathionine -Synthase Nitration

Figure 2

𝛼-Zearalanol treatment increased cystathionine 𝛽-synthase activity in the liver of HHcy rats. (a) The cystathionine 𝛽-synthase expression was detected by Western blot and normalized by GAPDH expression. (b) The cystathionine 𝛽-synthase activity was detected by enzyme linked chemiluminescent kit. Data were expressed as mean ± SD; 𝑛=3. Student 𝑡-test; **𝑃<0.01  versus HHcy. CBS: cystathionine 𝛽-synthase; HHcy: hyperhomocysteinemia; 𝛼-ZAL: 𝛼-zearalanol.

(a)

(b)