Integration of High-Volume Molecular and Imaging Data for Composite Biomarker Discovery in the Study of Melanoma

Table 3

Top-20 LDA features after 100 repetitions.

o.m	o.i	m.i top-means	nr.i top-means	nr.i top-20	nr.i top-20 freq.	u.i top-means	u.i top-20	u.i top-20 freq.	b.i top-means	b.i top-20	b.i top-20 freq.
ABCD1	I.mean	I.mean	HPCAL1.1	L.mean	78	HPCAL1.1	HPCAL1.1	75	CDC37L1	L.std	77
CRIM1.1	mean.R	mean.R	MMP1	mean.G	75	Grad.std	mean.B	69	MMP1	I.std	74
UPP1	mean.G	mean.G	CDC37L1	I.mean	71	CDC37L1	I.mean	63	HPCAL1.1	I.mean	70
GSTT1	mean.B	mean.B	C2orf68	I.std	70	Grad.mean	mean.G	61	ZSCAN18	mean.G	70
HPCAL1.1	A.mean	A.mean	A.mean	L.std	68	MMP1	Grad.std	59	C2orf68	L.mean	69
ZSCAN18	L.std	L.std	ID4	mean.B	63	ID4	L.std	59	ALOX12	A.mean	68
IFI16	I.std	I.std	ZSCAN18	std.B	61	SSBP2	std.B	58	PARD3	mean.B	67
SHARPIN	S.mean	S.mean	MTUS1	std.G	61	NRP2	I.std	57	ID4	mean.R	66
TMEM80	std.R	std.R	SSBP2	mean.R	60	IFT81	L.mean	56	MTUS1	S.mean	61
HOMER3.1	S.std	S.std	ALOX12	A.mean	59	FOXO1	CDC37L1	55	IFT81	std.B	61
PLAUR.1	A.std	A.std	NCAPH	GMSM.mean	54	ZSCAN18	A.mean	53	NCAPH	std.G	59
SNTB1	std.B	std.B	ANG	PERIMETER	54	RRAS2	B.std	53	NRP2	std.R	59
SFRP1.1	std.G	std.G	std.B	A.std	53	GPRIN2	std.G	52	CYP3A5.1	PERIMETER	58
MTUS1	B.mean	ABCD1	NRP2	HPCAL1.1	53	MTUS1	PERIMETER	51	SSBP2	DISSIMILARITY	54
RPRM	L.mean	B.mean	PARD3	S.mean	52	ALOX12	Grad.mean	49	ANG	A.std	50
FZD7	H.std	UPP1	CYP3A5.1	B.mean	50	mean.B	std.R	48	FOXO1	CDC37L1	50
SRC	H.mean	L.mean	ABCD1	std.R	50	NCAPH	A.std	45	C12orf29	GMSM.mean	49
MMP1	Distance.std	HPCAL1.1	BAZ1B	COMPLEXITY	48	NEIL1	mean.R	45	BAZ1B	B.std	47
LAMB4	PERIMETER	ZSCAN18	C12orf29	S.std	48	IFI16	DISSIMILARITY	44	ABCD1	B.mean	43
NEK2	COMPLEXITY	IFI16	IFT81	B.std	45	SLC7A8	S.mean	44	MAOA.1	COMPLEXITY	43