Table 1: Expression levels of core spindle assembly checkpoint components in oral squamous cell carcinoma.

SAC proteinSamplesExpression levelsReferences

Cdc20OSCC cell lines (7 out of 10)
Primary HNSCC (7 out of 10 cases)
Overexpression[58]
OSCC cell lines (2 of 7)Overexpression[59]
OSCC (37 out of 65 cases)Overexpression[61]

Mad2OSCC cell lines (7 out of 7)Underexpression[59]

BubR1OSCC (43 out of 43 cases)
Oral PMD (75 out of 77 cases)
Overexpression[62]
OSCCIS (15 out of 20 cases)
OSCCWT (19 out of 27 cases)
OSCCW (18 out of 23 cases)
Cervical LN (15 out of 23 cases)
Overexpression [63]
OLNM (16 out of 16 cases)Underexpression
OSCC (11 out of 49 cases)Overexpression[64]

Aurora BOSCC cell lines (7 out of 7)
OSCC (71 out of 101)
Overexpression[66]
OSCC (40 out of 40 cases)Overexpression[67]
OSCC (162 out of 215 cases)Overexpression[68]

PMD: potentially malignant disorders; OSCCIS: in situ OSCC; OSCCWT: invasive OSCC without metastasis; OSCCW: invasive OSCC with metastasis; cervical LN: lymph nodes; OLNM: nonmalignant oral lesions.