BioMed Research International / 2014 / Article / Tab 1

Review Article

MicroRNA as New Tools for Prostate Cancer Risk Assessment and Therapeutic Intervention: Results from Clinical Data Set and Patients’ Samples

Table 1

MicroRNAs associated with PCa diagnosis.

References Sample typemiRs deregulatedmiRs selected as candidate biomarkers

Taylor et al. (2010) [24]113 PCa tissues
28 normal tissues
Large screening studyTaylor et al. 10.1016/j.ccr.2010.05.026

Volinia et al. (2006) [31]56 PCa tissues
7 normal tissues
39 upregulated
6 downregulated
Volinia et al. 10.1073/pnas.0510565103;

Ambs et al. (2008) [32]60 microdissected tumor tissues
16 normal tissues
21 upregulated
21 downregulated
miR-32, miR-26a, miR-181a,
miR-93, miR-196a, miR25,
miR-92 and let-7i

Porkka et al. (2007) [38]5 hormone-naïve PCa tissues
4 HRPC tissues
4 BPH tissues
14 upregulated
37 downregulated
PCa: miR-16, miR-99 and let-7 family
HRPC: miR-205, miR-100 and miR-30

Ozen et al. (2008) [43]16 PCa tissues and 10 normal tissues9 upregulated
76 downregulated
Let-7, miR-30, miR-16

Martens-Uzunova et al. (2012) [44]102 PCa tissues and
normal adjacent tissues
54 deregulatedmiR-205

Larne et al. (2013) [45]49 PCa tissues
25 normal tissues
7 deregulatedmiR-96-5p, miR-183-5p
miR-145-5, miR-221-5p
(combined in miQ score)

Moltzahn et al. (2011) [46]Serum samples from PCa () and HD ()6 upregulated
4 downregulated
miR-20b, miR-874,
miR-1274a, miR-1207-5p,
miR-93, miR-106a
miR-223, miR-26b,
miR-30c, miR-24

Bryant et al. (2012) [48]Plasma samples from PCa () and HD ()
Urine samples from PCa () and HD ()
12 deregulatedmiR-107, miR-574-3p

Srivastava et al. (2013) [49]40 PCa tissues and 40 normal adjacent tissues.
Urine samples from PCa ()
and HD ()
2 downregulatedmiR-205, miR-214

Haj-Ahmad et al. (2014) [50] Urine samples from PCa ()
BPH () patients and HD ()
17 deregulated
(only 7 selected for further analysis)
miR-1825 (only in PCa)
miR-484 (in PCa and BPH)  

Schaefer et al. (2010) [54] 76 PCa and adjacent normal tissues 5 upregulated
10 downregulated
miR-96, miR-182, miR-182* 
miR-183 and miR-375
miR-16, miR-31, miR-125b,
miR-145, miR-149, miR-181b,
miR-184, miR-205, miR-221, miR-222

PCa: prostate cancer; HRPC: hormone refractory prostate cancer; BPH: benign prostatic hyperplasia; HD: healthy donors, FFPE: formalin-fixed, paraffin-embedded.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.