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References | Sample type | miRs deregulated | miRs selected as candidate biomarkers |
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Taylor et al. (2010) [24] | 113 PCa tissues 28 normal tissues | Large screening study | Taylor et al. 10.1016/j.ccr.2010.05.026 |
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Volinia et al. (2006) [31] | 56 PCa tissues 7 normal tissues | 39 upregulated 6 downregulated | Volinia et al. 10.1073/pnas.0510565103; |
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Ambs et al. (2008) [32] | 60 microdissected tumor tissues 16 normal tissues | 21 upregulated 21 downregulated | miR-32, miR-26a, miR-181a, miR-93, miR-196a, miR25, miR-92 and let-7i | ↑ |
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Porkka et al. (2007) [38] | 5 hormone-naïve PCa tissues 4 HRPC tissues 4 BPH tissues | 14 upregulated 37 downregulated | PCa: miR-16, miR-99 and let-7 family | ↓ |
HRPC: miR-205, miR-100 and miR-30 | ↓ |
|
Ozen et al. (2008) [43] | 16 PCa tissues and 10 normal tissues | 9 upregulated 76 downregulated | Let-7, miR-30, miR-16 | ↓ |
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Martens-Uzunova et al. (2012) [44] | 102 PCa tissues and normal adjacent tissues | 54 deregulated | miR-205 | ↓ |
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Larne et al. (2013) [45] | 49 PCa tissues 25 normal tissues | 7 deregulated | miR-96-5p, miR-183-5p | ↑ |
miR-145-5, miR-221-5p | ↓ |
(combined in miQ score) | |
|
Moltzahn et al. (2011) [46] | Serum samples from PCa () and HD () | 6 upregulated 4 downregulated | miR-20b, miR-874, miR-1274a, miR-1207-5p, miR-93, miR-106a | ↑ |
miR-223, miR-26b, miR-30c, miR-24 | ↓ |
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Bryant et al. (2012) [48] | Plasma samples from PCa () and HD () Urine samples from PCa () and HD () | 12 deregulated | miR-107, miR-574-3p | ↑ |
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Srivastava et al. (2013) [49] | 40 PCa tissues and 40 normal adjacent tissues. Urine samples from PCa () and HD () | 2 downregulated | miR-205, miR-214 | ↓ |
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Haj-Ahmad et al. (2014) [50] | Urine samples from PCa () BPH () patients and HD () | 17 deregulated (only 7 selected for further analysis) | miR-1825 (only in PCa) | ↑ |
miR-484 (in PCa and BPH) | ↓ |
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Schaefer et al. (2010) [54] |
76 PCa and adjacent normal tissues |
5 upregulated 10 downregulated | miR-96, miR-182, miR-182* miR-183 and miR-375 | ↑ |
miR-16, miR-31, miR-125b, miR-145, miR-149, miR-181b, miR-184, miR-205, miR-221, miR-222 | ↓ |
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