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BioMed Research International
Volume 2014, Article ID 146781, 16 pages
Research Article

Hot Melt Extruded Amorphous Solid Dispersion of Posaconazole with Improved Bioavailability: Investigating Drug-Polymer Miscibility with Advanced Characterisation

Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga, Mumbai, Maharashtra 400019, India

Received 13 February 2014; Revised 31 March 2014; Accepted 2 April 2014; Published 21 July 2014

Academic Editor: Frederic Lagarce

Copyright © 2014 Ritesh Fule and Purnima Amin. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The Supplementary Material is the Video of Extrusion Process of Pz1 Formulation Containing Drug and Polymer in 1:1 Ratio at Optimized Extrusion Parameters and Condition. This is Provided to Show the Morphology of Extruded Material which is in the Form of Glassy Dispersion (or Solid Solution).

  1. Supplementary Materials