Depressive Symptoms in Multiple Sclerosis from an In Vivo Study with TBSS

Table 2

The areas of FA value significantly reduced in WM by TBSS analysis.

		Talairach			𝑡 value	𝑉 mm^3
		𝑋	𝑌	𝑍
Limbic system
ACG	L	−7	24	−4	4.655	158
BA24	R	15	18	23	4.275	318
CG	L	−15	−33	35	5.154	1561
	R	19	−28	34	4.884	1798
PHG	L	−22	−18	−13	4.989	663
BA28/36	R	19	−41	2	5.884	654
PCG	L	−11	−56	6	2.974	125
BA29/30	R	14	−53	14	4.149	253
Subcortical
CC	IH	−1	−16	24	2.889	63
	L	−3	13	20	3.917	1180
	R	13	−29	25	6.924	1068
Insula	L	−38	−43	20	3.899	123
BA13	R	39	−41	19	4.562	107
Frontal lobe
CG	L	−17	15	36	3.727	38
PrG	L	−25	−17	50	2.299	30
BA4	R	37	−10	26	2.836	55
CC	L	−11	20	18	3.835	207
	R	13	19	20	3.922	146
Parietal
IPL	L	−42	−42	25	3.559	135
	R	38	−42	26	4.286	110
Precuneus	L	−21	−59	32	4.402	435
BA31	R	19	−42	44	5.347	271

BA: Brodmann area; ACG: anterior cingulate gyrus; CG: cingulate gyrus; PCG: posterior cingulate gyrus; MCG: middle cingulate gyrus; PMCG: posterior middle cingulate gyrus; CC: corpus callosum; IPL: inferior parietal lobule; PrG: precentral gyrus; DLPFC: dorsolateral prefrontal cortex; AG: angular gyrus; CL: cerebellar lingual; IH: interhemispheric; PHG: parahippocampal gyrus.