BioMed Research International / 2014 / Article / Tab 2

Research Article

GHK and DNA: Resetting the Human Genome to Health

Table 2

Ubiquitin/proteasome system and GHK.

UpGene titlePercent change in gene expression

1Ubiquitin specific peptidase 29, USP291056
2Ubiquitin protein ligase E3 component n-recognin 2, UBR2455
3Gamma-aminobutyric acid (GABA) B receptor, 1 /// ubiquitin D, GABBR1 /// UBD310
4Ubiquitin specific peptidase 34, USP34195
5Parkinson protein 2, E3 ubiquitin protein ligase (parkin), PARK2169
6Ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast), UBE2I150
7Ubiquitin protein ligase E3 component n-recognin 4, UBR4146
8Ubiquitin protein ligase E3B, UBE3B116
9Ubiquitin specific peptidase 2, USP2104
10Ubiquitin-like modifier activating enzyme 6, UBA6104
11Ubiquitination factor E4B (UFD2 homolog, yeast), UBE4B97
12Ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast), UBE2M92
13Ubiquitin-like modifier activating enzyme 7, UBA788
14HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1, HECW181
15Proteasome (prosome, macropain) 26S subunit, ATPase, 3, PSMC381
16Ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast), UBE2D179
17Proteasome (prosome, macropain) subunit, beta type, 2, PSMB279
18Ubiquitin protein ligase E3 component n-recognin 5, UBR577
19Ubiquitin specific peptidase 21, USP2176
20OTU domain, ubiquitin aldehyde binding 2, OTUB276
21Proteasome (prosome, macropain) inhibitor subunit 1 (PI31), PSMF175
22Ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast), UBE2H73
23Ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast), UBE2N72
24Ubiquitin carboxyl-terminal hydrolase L5, UCHL571
25Proteasome (prosome, macropain) 26S subunit, non-ATPase, 13, PSMD1370
26Ubiquitin associated protein 1, UBAP170
27Ubiquitin-conjugating enzyme E2B (RAD6 homolog), UBE2B69
28TMEM189-UBE2V1 readthrough /// ubiquitin-conjugating enzyme E2 variant 1, TMEM189-UBE2V1 /// UBE2V167
29Proteasome (prosome, macropain) 26S subunit, non-ATPase, 1, PSMD164
30Proteasome (prosome, macropain) 26S subunit, non-ATPase, 3, PSMD364
31Ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (drosophila), ARIH161
32BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase), BAP160
33Ubiquitin interaction motif containing 1, UIMC160
34Ubiquitin associated protein 2-like, UBAP2L57
35Ubiquitin protein ligase E3 component n-recognin 7 (putative), UBR756
36Ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast), UBE2G154
37Itchy E3 ubiquitin protein ligase homolog (mouse), ITCH54
38Ubiquitin-conjugating enzyme E2D 4 (putative), UBE2D451
39Proteasome (prosome, macropain) 26S subunit, non-ATPase, 10, PSMD1050
40WW domain containing E3 ubiquitin protein ligase 1, WWP150
41Ubiquitin-like 3, UBL350

DownGene titlePercent change in gene expression

1Ubiquitin associated and SH3 domain containing A, UBASH3A−89