Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: In Vitro and In Vivo Evaluation
Gamma scintigraphy images of anterior view (from left to right) of rat at 2 h time point after i.n. administration of -Lzp-PLGA-NPs (a), i.n. administration of -LS (b), and i.v. administration of -LS (c).