BioMed Research International / 2014 / Article / Fig 12

Research Article

Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: In Vitro and In Vivo Evaluation

Figure 12

(a) -Lorazepam concentration in rat blood at different time intervals following LS (i.v.), LS (i.n.), and Lzp-PLGA-NPs (i.n.) administration. (b) -Lorazepam concentration in rat brain at different time intervals following LS (i.v.), LS (i.n.), and lorazepam NPs (i.n.) administration.
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