Sinefungin, a Natural Nucleoside Analogue of S-Adenosylmethionine, Inhibits Streptococcus pneumoniae Biofilm Growth
Figure 2
Effect of sinefungin on pneumococcal in vitro biofilm growth. (a), (b) Pneumococcal biofilm growth with different concentrations of sinefungin for 18 h and detection of biofilm biomass by crystal-violet microtiter plate assay and CFU counts of pneumococcal biofilms. (c) and (d) show the effect of different concentrations of sinefungin on already established biofilms. (c) Detection of biofilm biomasses with crystal-violet microtiter assay. (d) CFU counts of pneumococcal biofilms. The error bars represent the standard deviation of the mean values. Significance was determined by Student’s -test (, ).
