Clinical Study

Levofloxacin-Amoxicillin/Clavulanate-Rabeprazole versus a Standard Seven-Day Triple Therapy for Eradication of Helicobacter pylori Infection

Table 3

Comparison of eradication rate and subgroup analysis.

Perprotocol analysisIntention-to-treat analysis
LAcR, (%)CAR, (%) valueOdd ratio (95% CI)LAcR, (%)CAR, (%) valueOdd ratio (95% CI)

All55 (80.9)42 (61.8)0.014*2.619
(1.20 5.70)
57 (78.1)42 (57.5)0.008*2.629 (1.28 5.42)
Age
 <60 years old 37 (75.5)31 (72.1)0.7101.194 (0.47~3.03)37 (72.5)31 (66.0)0.4791.364 (0.58~3.23)
 ≧60 years old20 (95.2)11 (42.3)0.000*27.273 (3.17~235)20 (90.9)11 (42.3)0.000*13.636 (2.62~70.91)
Gender
 Male30 (81.1)20 (64.5)0.1232.357 (0.78~7.11)30 (78.9)20 (60.6)0.0912.438 (0.86~6.94)
 Female25 (80.6)22 (59.5)0.0602.841 (0.94~8.59)27 (77.1)22 (55.0)0.044*2.761 (1.01~7.55)
Resident area
 Urban21 (77.8)16 (76.2)0.7481.094 (0.28~4.23)22 (73.3)16 (66.7)0.5941.375 (0.43~4.44)
 Rural34 (82.9)26 (55.3)0.006*3.923 (1.45~10.62)35 (81.4)26 (53.1)0.004*3.870 (1.50~10.02)
Endoscopic finding
 With peptic ulcer22 (75.9)22 (66.7)0.4261.571 (0.51~4.80)22 (73.3)22 (62.9)0.3681.625 (0.56~4.69)
 Without peptic ulcer 33 (84.6)20 (57.1)0.009*4.125 (1.38~12.36)35 (81.4)20 (52.6)0.006*3.938 (1.45~10.68)

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