Clinical Study
Levofloxacin-Amoxicillin/Clavulanate-Rabeprazole versus a Standard Seven-Day Triple Therapy for Eradication of Helicobacter pylori Infection
Table 3
Comparison of eradication rate and subgroup analysis.
| | Perprotocol analysis | Intention-to-treat analysis | | LAcR, (%) | CAR, (%) | value | Odd ratio (95% CI) | LAcR, (%) | CAR, (%) | value | Odd ratio (95% CI) |
| All | 55 (80.9) | 42 (61.8) | 0.014* | 2.619 (1.205.70) | 57 (78.1) | 42 (57.5) | 0.008* | 2.629 (1.285.42) | Age | | | | | | | | | <60 years old | 37 (75.5) | 31 (72.1) | 0.710 | 1.194 (0.47~3.03) | 37 (72.5) | 31 (66.0) | 0.479 | 1.364 (0.58~3.23) | ≧60 years old | 20 (95.2) | 11 (42.3) | 0.000* | 27.273 (3.17~235) | 20 (90.9) | 11 (42.3) | 0.000* | 13.636 (2.62~70.91) | Gender | | | | | | | | | Male | 30 (81.1) | 20 (64.5) | 0.123 | 2.357 (0.78~7.11) | 30 (78.9) | 20 (60.6) | 0.091 | 2.438 (0.86~6.94) | Female | 25 (80.6) | 22 (59.5) | 0.060 | 2.841 (0.94~8.59) | 27 (77.1) | 22 (55.0) | 0.044* | 2.761 (1.01~7.55) | Resident area | | | | | | | | | Urban | 21 (77.8) | 16 (76.2) | 0.748 | 1.094 (0.28~4.23) | 22 (73.3) | 16 (66.7) | 0.594 | 1.375 (0.43~4.44) | Rural | 34 (82.9) | 26 (55.3) | 0.006* | 3.923 (1.45~10.62) | 35 (81.4) | 26 (53.1) | 0.004* | 3.870 (1.50~10.02) | Endoscopic finding | | | | | | | | | With peptic ulcer | 22 (75.9) | 22 (66.7) | 0.426 | 1.571 (0.51~4.80) | 22 (73.3) | 22 (62.9) | 0.368 | 1.625 (0.56~4.69) | Without peptic ulcer | 33 (84.6) | 20 (57.1) | 0.009* | 4.125 (1.38~12.36) | 35 (81.4) | 20 (52.6) | 0.006* | 3.938 (1.45~10.68) |
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