Serum Soluble TACI, a BLyS Receptor, Is a Powerful Prognostic Marker of Outcome in Chronic Lymphocytic Leukemia

Table 1

Patients’ characteristics at the time of diagnosis.

Age, median (range)	60 years (37–82)
	For BLyS measurements	For sTACI measurements
	73	60
	%
Sex, M/F	61/39%	66/34%
Binet stage
1	59%	60%
2	34%	32%
3	7%	8%
Lymphadenopathy	60%	60%
Splenomegaly	18%	15%
Haemoglobin <10 g/dL	5.5%	8.3%
Platelet counts <100 × /L	2.7%	3.3%
Abnormal LDH	15%	15%
BM infiltration >50%	59%	50%
β2-Microglobulin >3.5 mg/L	30% (12/39 pts)	27% (9/33 pts)
Abnormal κ-sFLC (normal 3.3–19.4 mg/L)	30% (20/67 pts)	30%(17/56 pts)
Abnormal λ-sFLC (normal 5.71–26.3 mg/L)	8% (3/67 pts)	5% (3/56 pts)

FLC: free light chain.