New Biomarkers to Predict the Evolution of In Situ Breast Cancers

Table 3

Univariate analysis of different markers in tumor and stromal cells.

Markers	Tumor cells		Stroma
	OR (95% CI)	P	OR (95% CI)	P
TG2	0.47 (0.08–2.69)	0.397	0.95 (0.24–3.76)	0.236
HJURP	4.59 (0.90–23.25)	0.066	7.11 (1.00–50.74)	0.050
HIF-1α	3.05 (0.58–15.97)	0.187	9.90 (1.32–74.42)	0.026

Cut-offs: TG2 tumor cells (<70 versus ≥70), stroma (≥80 versus <80); HJURP tumor cells (≥70 versus <70), stroma (≥30 versus <30); HIF-1α tumor cells (≥4 versus <4), stroma (≥2 versus <2).