BioMed Research International / 2014 / Article / Tab 4

Review Article

N-Acyl Homoserine Lactone-Mediated Quorum Sensing with Special Reference to Use of Quorum Quenching Bacteria in Membrane Biofouling Control

Table 4

List of quorum quenching bacteria reported to degrade or modify AHLs.

Quenching bacteria Gene involvedAHLs degradedPhenotypes regulated Reference

AHL-acylase mediated QQ
Anabaena sp. PCC7120aiiC C4-HSL, 3-oxo-C4-HSL, 3-hydoxo-C4-HSL, 3-oxo-C6-HSL, 3-hydoxo-C6-HSL, C6-HSL, 3-oxo-C8-HSL, 3-hydoxo-C8-HSL, C8-HSL, 3-oxo-C10-HSL, 3-hydoxo-C10-HSL, C10-HSL, 3-oxo-C12-HSL, 3-hydoxo-C12-HSL, C12-HSL, 3-oxo-C14-HSL, 3-hydoxo-C14-HSL, and C14-HSLn.d.[106]

Acinetobacter sp. strain Ooi24UnknownC10-HSLn.d.[89]

B. pumilus S8-07Unknown3-Oxo-C12-HSLInhibit biofilm formation in P. aeruginosa PA01[107]

Comamonas strain D1UnknownC4-HSL, 3-oxo-C6-HSL, C6-HSL, 3-oxo-C8-HSL, C8-HSL, 3-oxo-C10-HSL, C10-HSL, 3-oxo-C12-HSL, C12-HSL, 3-oxo-C14-HSL, C14-HSL, and C16-HSLDecreases virulence and antibiotic production in Pec. carotovorum strain Pcc797[108]

P. aeruginosa quiP C6-HSL, C8-HSL, C10-HSL, and C12-HSLInhibits biofilm formation in Aeromonassp. [109]

P. aeruginosa PA01PA2385 3-Oxo-C12-HSLReduce virulence factor elastase and pyocyanin in P. aeruginosa PA01[73]

P. syringae strain B728ahacA C8-HSL, C10-HSL, and C12-HSLInfluence biofilm formation[110]

P. syringae strain B728ahacB 3-Oxo-C6-HSL, C6-HSL, C8-HSL, C10-HSL, 3-oxo-C12-HSL, and C12-HSLInfluence biofilm formation[110]

P. aeruginosa PAO1PA2385 C11-HSL, 3-oxo-C12-HSL, C12-HSL, 3-oxo-C14-HSL, and C14-HSLDecreases elastolytic activity and pyocyanin production[73]

Pseudomonas sp. strain PAI-ApvdQ C10-HSL, 3-oxo-C12-HSL, C12-HSL, and C14-HSLInhibit virulence factor [111]

P. aeruginosa PAO1quiP C8-HSL, C10-HSL, 3-oxo-C12-HSL, and C12-HSLInhibit virulence factor [112]

Pseudomonas sp. 1A1UnknownC6-HSL, C8-HSL, 3-oxo-C8-HSL, 3-oxo-C10-HSL, C10-HSL, 3-oxo-C12-HSL, and C12-HSLInhibit biofilm formation in MBR [113]

Rho. erythropolis strain W2Unknown C4-HSL, 3-oxo-C6-HSL, C6-HSL, C7-HSL, 3-oxo-C8-HSL, C8-HSL, and C10-HSLReduces pathogenicity of Pec. carotovorum  subsp. carotovorum in plants[114, 115]

Ralstonia sp. XJ12BaiiD 3-Oxo-C8-HSL, 3-oxo-C10-HSL, and 3-oxo-C12-HSLDecreases swarming ability and production of elastase and pyocyanin in P. aeruginosa PA01 [20]

Ralstonia solanacearum GMI1000aac C7-HSL, C8-HSL, 3-oxo-C8-HSL, and C10-HSLInhibits violacein and chitinase activity in C. violaceum CV026[116]

Streptomyces sp. strain M664ahlM C8-HSL, C10-HSL, and 3-oxo-C12-HSLDecreases virulence factor, elastase, protease, and LasA in P. aeruginosa [117]

Shewanella sp. strain MIB015aac C8-HSL, C10-HSL, and C12-HSLReduces biofilm formation in V. anguillarum [118]

Variovorax paradoxus strain VAI-CUnknownC4-HSL, 3-oxo-C6-HSL, C6-HSL, C8-HSL, C10-HSL, and C12-HSLn.d.[119]

AHL-lactonase mediated QQ
Ag. tumefaciens c58attM 3-Oxo-C8-HSLInhibit Ti plasmid conjugal transfer[120]

Ag. tumefaciens aiiB C4-HSL, 3-oxo-C6-HSL, C6-HSL, 3-oxo-C8-HSL, C8-HSL, and C10-HSLn.d.[121]

Ag. tumefaciens C58aiiB 3-Oxo-C6-HSL, C6-HSL, C8-HSL, C7-HSL, 3-oxo-C8-HSL, and C8-HSLReduces virulence of Erwinia strain 6276[122]

Ag. tumefaciens K84aiiS 3-Oxo-C6-HSL, C6-HSL,
3-oxo-C8-HSL, C8-HSL,
3-oxo-C10-HSL, C10-HSL, 3-oxo-C12-HSL, C12-HSL, 3-oxo-C14-HSL, and C14-HSL
n.d.[123, 124]

Acinetobacter sp. strain C1010UnknownC6-HSL, C8-HSLInhibit production of phenazines in P. chlororaphis O6 and virulence in Er. carotovora [125]

Acinetobacter sp. GG2Unknown3-Hydroxy-C4-HSL, C5-HSL, 3-hydroxy-C6-HSL, C6-HSL, C7-HSL, 3-oxo-C8-HSL, 3-hydroxy-C8-HSL, C8-HSL, C9-HSL, and 3-oxo-C10-HSL, 3-hydroxy-C10-HSL, C10-HSL, C11-HSL, 3-oxo-C12-HSL, 3-hydroxy-C12-HSL, C12-HSL, 3-oxo-C14-HSL, 3-hydroxy-C14-HSL, C14-HSL, Δ9-3-hydroxy-C14-HSL, Δ10-3-hydroxy-C14-HSL, Δ11-3-hydroxy-C14-HSL, and Δ13-3-hydroxy-C14-HSLAttenuates virulence of P. aeruginosa and Er. carotovora [109]

Acidobacteria sp.qIcA 3-Oxo-C6-HSL, C6-HSL, C7-HSL, 3-oxo-C8-HSL, C8-HSL, 3-oxo-C10-HSL, and C10-HSLDecreases virulence of Pec. carotovorum strain 6276[126]

Arthrobacter sp. IBN110ahlD C4-HSL, 3-oxo-C6-HSL, C6-HSL, C8-HSL, 3-oxo-C10-HSL, and C10-HSLDecreases virulence of Er. carotovora N98[127]

Bacillus sp. 240B1aiiA C8-HSLDecreases extracellular pectolytic enzyme activities and inhibits virulence in Er. carotovora [128, 129]

B. cereus aiiA C6-HSL, C8-HSL, and C10-HSLDecreases virulence factor[130]

B. mycoides aiiA C6-HSL, C8-HSL, and C10-HSLDecreases virulence factor[130]

Bacillus strain COT1aiiA 3-Oxo-C6-HSLDecreases virulence factor[130]

B. anthracis aiiA C6-HSL, C8-HSL, and C10-HSLDecreases swarming in Bur. thailandensis [131]

B. pumilus SW9Unknownn.d.Inhibit biofouling on microfiltration membranes by Brevundimonas sp. SW1, Acidovorax sp. DB3, Acinetobacter sp. GS1, and Staphylococcus aureus SA1[132, 133]

B. thuringiensis subspecies morrisoni aiiA 3-Oxo-C6-HSLAttenuates the pathogenicity of Er. carotovora [134]

B. thuringiensis aiiA 3-Oxo-C6-HSLDecreases virulence of Er. carotovora [135]

Bacillus sp. A24aiiA C4-HSL, C6-HSLDecreases production of elastase, rhamnolipids, and pyocyanin and inhibits swarming in P. aeruginosa PA01[136]

En. asburiae VT65aiiA C4-HSL, C6-HSL n.d.[137]

Geobacillus kaustophilus  strain HTA426GKL C4-HSL, 3-oxo-C6-HSL, C6-HSL, 3-oxo-C8-HSL, C8-HSL, C10-HSL, and 3-oxo-C12-HSLThermostable antivirulence therapeutic agent[138]

K. pneumonia ahlK C6-HSL, 3-oxo-C6-HSLDecreases virulence of Er. carotovora N98[127]

M. testaceum StLB018UnknownC6-HSL, 3-oxo-C6-HSL, C10-HSL, and 3-oxo-C10-HSLInterrupts pathogenicity of Pec. carotovorum subsp. carotovorum [139]

Mycobacterium avium subsp. paratuberculosis K-10MCP C7-HSL, C8-HSL, 3-oxo-C8-HSL, C10-HSL, and C12-HSLn.d.[140]

My. tuberculosis AhlA, PPH C4-HSL, 3-oxo-C8-HSL, and C10-HSLn.d.[141]

M. testaceum StLB037aiiM 3-Oxo-C6-HSL, C6-HSL,
3-oxo-C8-HSL, C8-HSL,
3-oxo-C10-HSL, and C10-HSL
Reduces pectinase activity and virulence in Pec. carotovorum subsp. carotovorum [142]

Ochrobactrum sp. T63aidH C4-HSL, C6-HSL, 3-oxo-C6-HSL, 3-oxo-C8-HSL, and C10-HSLReduce biofilm formation by P.  fluorescens 2P24 and the pathogenicity of Pec. carotovorum [143]

Pichia pastoris aiiA B5463-Oxo-C6-HSL, C6-HSL, 3-oxo-C8-HSL, C8-HSL, C10-HSL, and C12-HSLAttenuates the A. hydrophila infection in aquaculture[144]

Pseudoalteromonas byunsanensis strain 1A01261qsdH C4-HSL, 3-oxo-C6-HSL, C6-HSL, 3-oxo-C8-HSL, C8-HSL, C10-HSL, C12-HSL, and C14-HSLAttenuates the plant pathogenicity of Er. carotovora [145]

Rho. erythropolis W2qsdA 3-Oxo-C6-HSL, C6-HSL,
3-oxo-C8-HSL, C8-HSL,
3-oxo-C10-HSL, C10-HSL, 3-oxo-C12-HSL, C12-HSL, 3-oxo-C14-HSL, and C14-HSL
Decreases virulence of Pec. carotovorum strain PCC797[146]

Rhodococcus strain LS31UnknownC6-HSL, 3-oxo-C6-HSL, C10-HSL, and 3-oxo-C10-HSLReduces pectate lyase activity in Er. carotovora [147]

Rhodococcus strain PI33UnknownC6-HSL, C10-HSLReduces pectate lyase activity in Er. carotovora [147]

Rhodococcus sp. BH4qsdA 3-Oxo-C6-HSL, C6-HSL, 3-oxo-C8-HSL, C8-HSL, 3-oxo-C10-HSL, C10-HSL, 3-oxo-C12-HSL, and C12-HSLInhibit biofilm formation in MBR[148, 149]

Rhodococcus sp. A167UnknownC6-HSL, 3-oxo-C8-HSL, and C8-HSLAttenuates maceration ability of Pec. carotovorum subsp. carotovorum [150]

Solibacillus silvestris StLB046ahlS C10-HSLAttenuates maceration of plant pathogen Pec. carotovorum subsp. carotovorum [151]

Thalassomonas sp. PP2-459UnknownC4-HSL, C6-HSL, C8-HSL, 3-oxo-C10-HSL, C10-HSL, and C12-HSLDecreases pathogenicity of V. anguillarum ATCC 19264[152]

Oxidoreductase mediated QQ
B. megaterium  CYP102A1P450BM3 Oxidizes; C12-HSL, 3-oxo-C12-HSL, C14-HSL, 3-oxo-C14-HSL, C16-HSL, C18-HSL, and C20-HSL.n.d.[153]

Rho. erythropolis W2UnknownOxidizes; 3-oxo-C10, 3-oxo-C12-HSLn.d.[115]

n.d.: not determined.