Sulfa Drugs as Inhibitors of Carbonic Anhydrase: New Targets for the Old Drugs

Figure 3

Compound 5a inside binding pocket of hCA II. 5a is shown in magenta color with sticks representation. The hydrophobic surfaces are drawn using Chimera and the color scheme is according to Kyte-Doolittle coloring scheme; blue color indicates most hydrophilic surface (hence polar residues), white for neutral, and orange for hydrophobic surface (nonpolar residues).