Sulfa Drugs as Inhibitors of Carbonic Anhydrase: New Targets for the Old Drugs

<div>Synthesis of 2,4,6-trichloro-1,3,5-triazine (TCT) derivatives (<b>1a</b>–<b>5a</b>) of sulfa drugs sulfamerazine (<b>1b</b>), sulfaquinoxaline (<b>2b</b>), sulfadiazine (<b>3b</b>), sulfadimidine (<b>4b</b>), and sulfachloropyrazine (<b>5b</b>), respectively<b>.</b></div>

BioMed Research International

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Scheme 1

Scheme 1: Sulfa Drugs as Inhibitors of Carbonic Anhydrase: New Targets for the Old Drugs 