Research Article
Histologic Changes of Implanted Gore Bio-A in an Experimental Animal Model
Table 2
Microscopic findings according to the duration of Gore Bio-A implantation.
| | | Inflammatory cell infiltration* | Connective tissue ingrowth | Collagen deposition | Foreign body reaction | Neovascularization |
| | 1 month ((a)/(b)) | | | | | | | 1-layer | 0/1 | 3/3 | 2/3 | 3/3 | 2/1 | | 2-layer | 0/0 | 2/2 | 2/3 | 3/3 | 2/2 | | 3-layer | 0/1 | 3/3 | 3/3 | 3/3 | 3/2 | | 4-layer | 2/1 | 1/3 | 1/3 | 1/3 | 1/2 | | 5-layer | 1/1 | 3/3 | 3/3 | 3/3 | 3/2 | | 3 months ((c)/(d)) | | | | | | | 1-layer | 0/0 | 3/2 | 3/1 | 3/1 | 3/1 | | 2-layer | 0/0 | 2/2 | 1/1 | 3/2 | 2/2 | | 3-layer | 0/0 | 2/2 | 1/1 | 3/2 | 2/2 | | 4-layer | 0/1 | 2/2 | 1/1 | 3/2 | 2/2 | | 5-layer | 0/1 | 2/2 | 3/2 | 3/2 | 1/2 | | 6 months ((e)/(f)) | | | | | | | 1-layer | 1/1 | 3/3 | 1/1 | 2/1 | 1/1 | | 2-layer | 1/1 | 3/3 | 0/0 | 3/2 | 1/1 | | 3-layer | 1/1 | 3/3 | 0/0 | 2/1 | 1/1 | | 4-layer | 1/1 | 3/3 | 0/0 | 3/2 | 1/1 | | 5-layer | 1/1 | 3/3 | 1/0 | 2/3 | 1/1 |
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Scoring: 0: negative; 1: mild; 2: moderate; 3: severe.
*0: no inflammatory cell infiltration; 1: focal inflammatory cell infiltration; 2: acute suppurative inflammation.
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