Risk Factors for Mortality in Patients with Septic Acute Kidney Injury in Intensive Care Units in Beijing, China: A Multicenter Prospective Observational Study
Table 1
Patient characteristics.
Survivors ()
Nonsurvivors ()
value
Age (years; median IQR)
72 (56–81)
78 (67–83)
<0.001
Gender (male) (%)
131/201 (65.17%)
100/160 (62.50%)
0.264
BMI (mean ± SD)
23.50 ± 3.56
22.73 ± 4.09
0.058
Hospital acquired infection (%)
61/201 (30.35%)
75/160 (46.88%)
0.001
Admission, (%)
Surgical admission
38/201 (18.91%)
14/160 (8.75%)
0.004
Emergency
83/201 (41.29%)
56/160 (35%)
0.003
Duration in ICU
Days in ICU (days; median [IQR])
9 (5–16)
9 (5–19)
0.737
Nonrenal organ failure, (%)
Respiratory failure
124/201 (61.69%)
112/160 (70%)
0.099
Systolic heart failure
11/201 (5.47%)
22/160 (13.75%)
0.007
Hypovolemia shock
17/201 (8.46%)
19/160 (11.88%)
0.282
Septic shock
80/201 (39.8%)
68/160 (42.50%)
0.604
DIC
13/201 (6.47%)
8/160 (5.00%)
0.554
Hepatic failure
12/201 (5.97%)
8/160 (5.00%)
0.500
MODS (nonrenal)
62/201 (30.85%)
65/160 (40.63%)
0.051
Comorbid disease, (%)
Malignancy
34/201 (16.92%)
43/160 (26.88%)
0.031
Hypertension/CHD
108/201 (53.73%)
94/160 (58.75%)
0.340
Diabetes mellitus
48/201 (23.88%)
33/160 (20.63%)
0.461
CKD without renal failure
11/201 (5.47%)
4/160 (2.50%)
0.160
CKD with renal failure
19/201 (9.45%)
21/160 (13.13%)
0.269
Immunosuppression
9/201 (4.48%)
7/160 (4.38%)
0.586
Organ transplant
5/201 (2.49%)
2/160 (1.25%)
0.47
Heart function level IV
14/201 (6.97%)
23/160 (14.36%)
0.021
APACHEII score, first 24 h in ICU (mean ± SD)
21.41 ± 7.74
26.32 ± 7.15
<0.001
SOFA score, first 24 h in ICU (mean ± SD)
9.42 ± 5.33
11.83 ± 5.21
<0.001
BMI: body mass index, RRT: renal replacement therapy, CKD: chronic kidney disease, ICU: intensive care unit, DIC: disseminated intravascular coagulation, MODS: multiple organ dysfunction syndrome, CHD: chronic heart disease, SOFA: sequential organ failure assessment, APACHE: acute physiology and chronic health evaluation.
