Risk Factors for Mortality in Patients with Septic Acute Kidney Injury in Intensive Care Units in Beijing, China: A Multicenter Prospective Observational Study
Table 4
Regression analysis of risk factors for mortality in ICU.
Univariate analysis
Multivariate analysis
OR (95% CI)
value
OR (95% CI)
value
Age (years)
1.026 (1.012–1.041)
<0.001
1.025 (1.007–1.042)
0.005
Hospital acquired infection
2.025 (1.314–3.120)
0.001
Nonrenal organ failure
Systolic heart failure
2.754 (1.293–5.866)
0.009
Comorbid disease
Malignancy
1.748 (1.050–2.911)
0.032
Heart function IV
2.242 (1.114–4.516)
0.024
APACHE II score
1.092 (1.059–1.129)
<0.001
1.072 (1.037–1.109)
<0.001
SOFA score
1.090 (1.046–1.135)
<0.001
0.952 (0.889–1.020)
0.160
Mechanical ventilation
Patients on mechanical ventilation
2.703 (1.543–4.737)
0.001
Duration on mechanical ventilation
1.136 (1.071–1.206)
<0.001
1.080 (1.008–1.158)
0.03
Fluid management
Daily fluid balance (mL/24 h)
1.000 (1.000–1.001)
0.001
Hemodynamic data
Duration for MAP < 65 mmHg
1.195 (1.083–1.319)
<0.001
1.149 (1.032–1.279)
0.011
Vasoactive agents
Vasopressors
1.211 (1.126–1.302)
<0.001
1.082 (0.985–1.188)
0.102
RRT
Need for RRT (%)
1.825 (1.180–2.822)
0.007
Time until RRT started (days)
1.261 (1.146–1.388)
<0.001
1.238 (1.115–1.374)
<0.001
Worst KDIGO
Stage 1 (%)
0.379 (0.216–0.665)
0.001
Stage 2 (%)
0.625 (0.384–1.019)
0.060
Stage 3 (%)
2.645 (1.718–4.073)
<0.001
1.466 (0.822–2.613)
0.195
Progress KDIGO class
Progressive AKI
3.341 (2.039–5.475)
<0.001
3.374 (1.918–5.933)
<0.001
OR: odd ratio; APACHE II score, first 24 h in ICU; SOFA score, first 24 h in ICU.
