1,3,4-Oxadiazole Derivatives: Synthesis, Characterization, Antimicrobial Potential, and Computational Studies

Table 4

Minimum inhibitory concentrations (MIC) of synthesized 1,3,4-oxadiazole derivatives.

Compound	MIC (𝜇g/mL)
	E.  coli	P. aeruginosa	S.  aureus	S.  epidermidis	C.  albicans	A.  niger
6a	50	100	50	200	50	100
6b	50	200	50	100	25	200
6c	25	200	100	100	200	50
6d	200	200	100	200	200	100
6e	25	100	25	100	200	50
6f	12.5	100	100	12.5	12.5	25
6g	50	100	100	50	25	25
6h	25	100	50	25	50	200
13a	25	200	25	50	50	50
13b	12.5	12.5	100	12.5	12.5	10
13c	25	25	100	25	25	10
13d	25	25	50	50	50	50
13e	12.5	25	25	25	100	10
13f	50	50	100	25	25	25
13g	50	25	50	50	50	100
13h	50	100	200	25	100	200
Control	—	—	—	—	—	—
Amoxicillin	12.5	200	100	12.5	—	—
Cefixime	50	400	400	50	—	—
Fluconazole	—	—	—	—	12.5	400