Expression of EpCAM Increases in the Hepatitis B Related and the Treatment-Resistant Hepatocellular Carcinoma
EpCAM-positive cells of PLC/PRF/5 had anticancer drug resistance potency. (a) Flow-cytometric analysis of various surface molecules in HCC cell lines. Percentages of the indicated molecule-positive cells are indicated. A representative result of three independent staining experiments is shown. (b)-(c) PLC/PRF/5 were exposed to various doses of cisplatin for 24 hr. The results of flow-cytometoric analysis are shown. The average of 3 independent experiments is shown with SD. (d) The cell viability was determined by MTS cell proliferation assay after exposure to various doses of cisplatin. The average of 3 independent experiments is shown with S.E.M.