p53 Is a Key Regulator for Osthole-Triggered Cancer Pathogenesis
Figure 2
Osthole inhibits migration activity of human colon cancer. By using cell culture insert system, migratory activities of human colon cancer cells were examined. After incubating cells with osthole (10 μM) or vehicle control for 24 h, we found that osthole inhibited migration activity in both HCT116 (a) and SW480 (b) cells. Migrated cells were visualized by phase-contrast imaging (right panels). Results are expressed as means ± S.E.M. from three independent experiments. , compared with control group.
