Research Article

Proteomics Analysis for Finding Serum Markers of Ovarian Cancer

Table 2

Serum proteins differentially expressed between patients with ovarian cancer and healthy individuals.

Protein IDProtein nameOC/HCMass

Upregulated
IPI00657670AHSG alpha-2-HS-glycoprotein precursor2.0 40098
IPI00022434ALB isoform 1 of serum albumin precursor1.1 71317
IPI00021841APOA1 apolipoprotein A-I precursor1.6 30759
IPI00021854APOA2 apolipoprotein A-II precursor2.4 11282
IPI00847179APOA4 apolipoprotein A-IV precursor2.4 45344
IPI00022229APOB apolipoprotein B-100 precursor2.2 516666
IPI00021855APOC1 apolipoprotein C-I precursor2.0 9326
IPI00021857APOC3 apolipoprotein C-III precursor1.8 10846
IPI00006662APOD apolipoprotein D precursor1.9 21547
IPI00021842APOE apolipoprotein E precursor2.1 36246
IPI00186903APOL1 isoform 2 of apolipoprotein-L1 precursor2.0 45957
IPI00030739APOM apolipoprotein M4.5 21582
IPI00006608APP isoform APP770 of amyloid beta A4 protein precursor 2.0 87914
IPI00027507ARFIP1 isoform B of arfaptin-13.0 41770
IPI00218982BRCA1 breast cancer type 1 susceptibility protein5.8 210101
IPI00075013C1QTNF1 complement C1q tumor necrosis factor-related protein 1 precursor2.2 32065
IPI00186808CFHR5 complement factor H-related 52.4 69411
IPI00552578CFP properdin precursor3.0 53751
IPI00400826CLU clusterin isoform 11.1 58537
IPI00013212CSK tyrosine-protein kinase CSK2.3 51242
IPI00032311DADB-112B14.11 complement component 4B1.5 194167
IPI00328249EIF2AK1 isoform 1 of eukaryotic translation initiation factor 2-alpha kinase 11.9 71632
IPI00296534FBLN1 isoform D of fibulin-1 precursor1.6 81315
IPI00293925FCN3 isoform 1 of ficolin-3 precursor3.7 33395
IPI00021891FGG isoform gamma-B of fibrinogen gamma chain precursor2.5 52106
IPI00298497FN1 isoform 1 of fibronectin precursor1.2 266034
IPI00555812GC vitamin D-binding protein precursor4.5 54526
IPI00025426GPX3 glutathione peroxidase 3 precursor1.8 25774
IPI00012391HABP2 hyaluronan-binding protein 2 precursor2.8 64740
IPI00299435HBA1; HBA2 hemoglobin subunit alpha3.0 45371
IPI00218660HSPG2 basement membrane-specific heparan sulfate proteoglycan core protein precursor1.0479248
IPI00021885IGKV1-5 IGKV1-5 protein1.2 26034
IPI00383338ITIH1 inter-alpha-trypsin inhibitor heavy chain H1 precursor1.1 10178
IPI00000075LGALS3BP galectin-3-binding protein precursor2.9 66202
IPI00029168LPA lysophosphatidic acid2.0 514737
IPI00220249LTBP1 latent-transforming growth factor beta-binding protein2.0 180984
IPI00294842MASP Mannan-binding lectin serine protease 2.0 21129
IPI00743335MYO1C myosin IC isoform a2.0 122461
IPI00022446PF4 platelet factor 4 precursor5.0 11123
IPI00019580PLG plasminogen precursor3.1 93247
IPI00025190PON1 serum paraoxonase/arylesterase 11.1 39895
IPI00022445PRG4 isoform A of proteoglycan-4 precursor4.0 152238
IPI00015614PRSS3 isoform A of trypsin-3 precursor2.0 33276
IPI00022420RBP4 plasma retinol-binding protein precursor3.0 23337
IPI00019399SAA4 serum amyloid A-4 protein precursor4.5 14854
IPI00629921SERPING1 plasma protease C1 inhibitor precursor3.1 55347
IPI00019176SPP2 secreted phosphoprotein 24 precursor3.2 24607
IPI00020194TAF15 isoform Short of TATA-binding protein-associated factor2.2 61749
IPI00296099THBS1 thrombospondin-1 precursor1.7 133291
IPI00018769THBS2 thrombospondin-2 precursor1.8 133749
IPI00022432TTR transthyretin precursor3.7 15991
IPI00298971VTN vitronectin precursor1.8 55069

Downregulated
IPI00021812AHNAK neuroblast differentiation-associated protein AHNAK0.2 629213
IPI00020567ARHGAP1 Rho GTPase-activating protein 10.1 50461
IPI00294834ASPH aspartyl/asparaginyl beta-hydroxylase0.3 86266
IPI00479116CPN2 carboxypeptidase N subunit 2 precursor0.5 61431
IPI00074148DST dystonin isoform 10.1 632532
IPI00003351ECM1 extracellular matrix protein 1 precursor0.4 62232
IPI00178352FLNC isoform 1 of filamin-C0.6 293344
IP00022479HERC1 probable E3 ubiquitin-protein ligase HERC10.1 538918
IPI00550090JMJD3 jumonji domain containing 3, histone lysine demethylase0.4 182243
IPI00398728RP1L1 isoform 1 of retinitis pigmentosa 1-like 1 protein0.1 263287
IPI0006146SAA2 serum amyloid A2 isoform a0.3 11277
IPI00027191SAA3P putative serum amyloid A-3 protein0.1 13489
IPI00553177SERPINA1 isoform 1 of alpha-1-antitrypsin precursor0.7 46878
IPI00470627SHPRH SNF2 histone linker PHD RING helicase isoform a0.5 195906