Sensitivities, Specificities, and Predictive Values of Microbiological Culture Techniques for the Diagnosis of Prosthetic Joint Infection

Table 1

New definition for periprosthetic joint infection: from the workgroup of the Musculoskeletal Infection Society [19].

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The presence of a major factor:

 (1) Sinus tract communicating with the prosthesis;

 (2) Pathogen isolated by culture from 2 or more separate tissue or fluid samples.

The presence of 4 out of the 6 minor factors:

 (1) Elevated erythrocyte sedimentation rate and serum C-reactive protein concentration;

 (2) Elevated synovial white blood cell count;

 (3) Elevated synovial polymorphonuclear percentage;

 (4) Presence of purulence in the affected joint;

 (5) Isolation of a microorganism in one culture of periprosthetic tissue or fluid;

 (6) Greater than 5 neutrophils per high power field.

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