Unexpected Lack of Deleterious Effects of Uranium on Physiological Systems following a Chronic Oral Intake in Adult Rat
Figure 6
Effects of uranium on cytokine gene and protein expression in rat intestine. Expression was measured in samples from control animals (NC: noncontaminated) and animals contaminated by uranium (U) in their drinking water at various concentrations (0.2, 2, 20, or 120 mg/L). Data are mean ± SD of 9-10 animals. (a) Gene expression: the mRNA levels are expressed as a ratio to the reference gene HPRT (hypoxanthine-guanine phophoribosyltransferase, a housekeeping gene). (b) Protein expression: tissue protein levels are expressed in pg/mg protein. *: significantly different from control values.: significantly different from the U 0.2 mg/L group. #: significantly different from the U 20 mg/L group.
