Glioprotective Effects of Ashwagandha Leaf Extract against Lead Induced Toxicity
(a) NCAM protein expression levels were determined by immunostaining in control (C), ASH-WEX (0.1%) pretreatment (CA), lead nitrate (200 μM, LN), and lead nitrate after pretreatment with ASH-WEX (LN + AS) treated groups. Lead treatment resulted in decreased expression of NCAM in LN group which was normalized by ASH-WEX pretreatment as shown in LN + AS group cells. These changes were also evident at transcription levels. (b) depicts representative RT-PCR products for the mRNA expression levels of NCAM and β-actin.
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