Evaluation of the Antioxidant Activity and Antiproliferative Effect of the Jaboticaba (Myrciaria cauliflora) Seed Extracts in Oral Carcinoma Cells
Figure 3
Apoptosis induction by jaboticaba seed water extract treatment of HSC-3 cells. (a) HSC-3 cells treated with jaboticaba seed water extract for 24 h at desired concentrations were stained with Annexin V-FITC and propidium iodide (PI). The Annexin V-FITC signal is shown on the x-axis and PI signal is shown on the y-axis. The apoptotic populations of cells were significantly increased in treatment groups in a dose-dependent manner. (b) Flow cytometric analysis was performed after a 48 h treatment to determine caspase-3 activity, which was found to be activated in a dose-dependent manner.
