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BioMed Research International
Volume 2014, Article ID 186864, 12 pages
http://dx.doi.org/10.1155/2014/186864
Review Article

A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

1Biomolecular Research Group, Biochemistry Program, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
2Tropical Infectious Disease Research and Education Center (TIDREC), Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
3Department of Chemistry, Faculty of Sciences, Guilan University, Rasht, Iran
4Persian Gulf Marine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr 3631, Iran

Received 21 January 2014; Accepted 28 March 2014; Published 29 April 2014

Academic Editor: José Carlos Tavares Carvalho

Copyright © 2014 Soheil Zorofchian Moghadamtousi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Curcuma longa L. (Zingiberaceae family) and its polyphenolic compound curcumin have been subjected to a variety of antimicrobial investigations due to extensive traditional uses and low side effects. Antimicrobial activities for curcumin and rhizome extract of C. longa against different bacteria, viruses, fungi, and parasites have been reported. The promising results for antimicrobial activity of curcumin made it a good candidate to enhance the inhibitory effect of existing antimicrobial agents through synergism. Indeed, different investigations have been done to increase the antimicrobial activity of curcumin, including synthesis of different chemical derivatives to increase its water solubility as well ass cell up take of curcumin. This review aims to summarize previous antimicrobial studies of curcumin towards its application in the future studies as a natural antimicrobial agent.