Research Article

Genome-Wide Uncovering of STAT3-Mediated miRNA Expression Profiles in Colorectal Cancer Cell Lines

Figure 3

Interaction of miRNAs and their potential targets. (a) Upregulated miRNAs in SW480/STAT3-siRNA cells. (b) Selected target genes mediated by multiple miRNAs. The genes in upper box are predicted to be potential targets of ≥14 miRNAs from upregulation group; the bottom box shows that four genes are targeted by ≥12 miRNAs from the downregulation group. (c) Downregulated miRNAs in SW480/STAT3-siRNA cells. Heat map illustrates maximum (red) and minimum (blue) miRNA expression levels.
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