In Silico Investigation of Potential Pyruvate Kinase M2 Regulators from Traditional Chinese Medicine against Cancers

Figure 2

Binding site of PKM2 protein defined as the volume of 𝑁-(4-((4-(pyrazin-2-yl)piperazin-1-yl)carbonyl)phenyl)quinoline-8-sulfonamide and root-mean-square deviation value between crystallized structure (orange) and docking pose (violet).