Research Article

Effect of Cyclic Mechanical Stimulation on the Expression of Osteogenesis Genes in Human Intraoral Mesenchymal Stromal and Progenitor Cells

Figure 3

Regulation of osteogenesis-specific markers under the influence of mechanical stimulation. mRNA levels of (a) RUNX2, (b) Col1A1, (c) SPP1, (d) BGLAP, (e) BMP2, and (f) SPARC were normalized to their respective mechanically unstimulated control groups. EX(−) represents the undifferentiated mechanically unstimulated group, EX(+) the undifferentiated mechanically stimulated group, OG(−) the osteogenic differentiated mechanically unstimulated group, and OG(+) the osteogenic differentiated mechanically stimulated group. The values are of independent experiments performed in triplicate ( ); * .
189516.fig.003a
(a)
189516.fig.003b
(b)
189516.fig.003c
(c)
189516.fig.003d
(d)
189516.fig.003e
(e)
189516.fig.003f
(f)