Diverse Effects of ANXA7 and p53 on LNCaP Prostate Cancer Cells Are Associated with Regulation of SGK1 Transcription and Phosphorylation of the SGK1 Target FOXO3A
Figure 4
Aberrant SGK1 isoforms in LNCaP compared to DU145. (a) SGK1 cDNA from LNCaP and DU145 was sequenced and aligned with wild-type SGK1 reference. The alignment image shows the missing exon11 in LNCaP (red dotted line) and the G/C-change in DU145. (b) SGK1 isoform in LNCaP is designated by an arrow. Both cells are represented by controls only (parental and vector alone as 1 and 2, resp.).
